Drug Formulations Manual Fourth Edition

AUTHOR'S: D. P. S. Kohli and D. H. Shah
ISBN: 9788190646772
YEAR: 2012
PAGES: 506
BINDING: Hard
LANGUAGE: English

ABOUT THE BOOK

Pharmaceutical formulation involves development of a bio available, stable and optimal dosage form for a specific administration route,and successful formulation development takes more than a great idea. It takes technology, know-how and manufacturing experience to find the best route for your product. It also takes regulatory expertise, a commitment from a team of dedicated people and cGMP assets to meet your needs from development through commercial launch. The goal of this book is to assist the reader in identifying the best form of delivery and the most viable manufacturing process for their product. Factors playing a role in development of a dosage form manufacturing process include manufacturability, consistency of products' quality, batch size optimization, yield improvement, SKU reduction and cost optimization. Over five decades of manufacturing experience of each of the authors, ensures that this book can shed new light on how to get your products to market quickly, efficiently and in a cost effective manner.AII formulations are validated and based on actual production batches undertaken in various manufacturing facilities.Information on each product is covered under the following heads: Labeled Formula, Batch Size, Practical Yield, Ingredients and Batch Quantities, Manufacturing Specifications and Manufacturing Processes.
There are over four hundred products in this book covering major categories of pharmaceutical formulations:
• Solid dosage formulations (capsules, tablets for immediate release or extended release)
• Non-sterile liquid formulations for oral administration (syrups, suspensions)
• Sterile liquid dosage formulations (ophthalmic, oral, nasal)
• Injectables drugs (intravenous, and intramuscular, subcutaneous injectables)
• Topical formulations (creams, gels)

ABOUT THE AUTHOR'S

1. D.P.S. Kohli graduated in Pharmacy in 1954 with decades of practical manufacturing experience of drug formulations behind him. He also worked as a Pharmaceutical Consultant having set up over 50 drug formulation factories.
2. D.H. Shah graduated in Pharmacy in 1962 and was associated with the manufacture of all categories of drug formulations for more than 40 years.

CONTENTS

A. INTRODUCTION
B. PRACTICAL TIPS
C. SOME COMMON PROBLEMS IN TABLETING
D. LIST OF BINDERS AND LUBRICANTS
E. FORMULATIONS
1. Acarbose Tablets
2. Albendazole Tablets
3. Albendazole Chewable Tablets 400 mg
4. Alprazolam Tablets 0.25 mg
5. Alprazolam Tablets 0.5 mg
6. Alprazolam Tablets 1 mg
7. Aluminium Hydroxide and Magnesium Trisilicate Tablets
8. Aluminium Hydroxide, Magnesium Hydroxide and Simethicone Tablets
9. Aminophylline Tablets
10. Amiodarone Tablets 100 mg
11. Amiodarone Tablets 200 mg
12. Amitryptyline Tablets 50 mg
13. Amlodipine Tablets
14. Amoxycillin Dispersible Tablets 125 mg
15. Amoxycillin Dispersible Tablets 250 mg
16. Amoxycillin Tablets
17. Amoxycillin Trihydrate and Clavulanate Tablets
18. Ampicillin, Cloxacillin and Lactobacillus Sporogenes Dispersible Tablets
19. Analgin and Dicyclomine Hydrochloride Tablets - I
20. Analgin and Dicyclomine Hydrochloride Tablets - II
21. Analgin Tablets
22. Ascorbic Acid Tablets 100 mg
23. Ascorbic Acid Tablets 500 mg
24. Aspirin, Paracetamol and Caffeine Tablets
25. Asprin, Chlorpheniramine Maleate and Phenylepherine Hydrochloride Tablets
26. Aspirin Tablets 300 mg
27. Atenolol Tablets 100mg
28. Atenolol Tablets 50 mg
29. Atorvastatin Tablets
30. Azithromycin Tablets 250 mg
31. B. Complex With Vitamin C Tablets
32. Betamethasone Tablets 0.5 mg
33. Betamethasone and Dexchlorpheniramine Maleate Tablets....
34. Calcium and Vitamin D Tablets
35. Calcium, Vitamin D3 and L-Lysine Monohydrochloride Tablets
36. Captopril Tablets
37. Carbamazepine Tablets (Chewable Tablets)
38. Carbamazepine Tablets 250 mg
39. Cefadroxil Dispersible Tablets 125 mg
40. Cefadroxil Dispersible Tablets 250 mg
41. Cefadroxil Tablets 500 mg
42. Cetrizine and Pseudoephedrine Delayed Release Tablets
43. Chloroquin Phosphate Tablets
44. Chlorpheniramine Maleate Tablets
45. Chlorpromazine Tablets
46. Cimetidine Tablets 200 mg
47. Ciprofloxacin Tablets
48. Ciprofloxacin and Tinidazole Tablets
49. Clopidogrel Tablets
50. Compound Magnesium Trisilicate Chewable Tablets
51. Co-Trimoxazole Tablets
52. Co-Trimoxazole Tablets D.S
53. Dapsone Tablets 50 mg
54. Dexamethasone Tablets - I
55. Dexamethasone Tablets - II
56. Diazepam Tablets
57. Diclofenac Sustained Release Tablets 100 mg
58. Diclofenac Tablets 50 mg
59. Diethylycarbamazine Tablets
60. Digoxin Tablets
61. Domperidone Tablets 10 mg
62. Doxycycline Hydrochloride Tablets 100 mg
63. Drotaverine Hydrochloride Tablets
64. Enalapril Tablets
65. Enalapril Maleate Tablets 2.5 mg
66. Enalapril Maleate Tablets 5 mg
67. Ephedrine Hydrochloride Tablets
68. Erythromycin Tablets 100 mg
69. Erythromycin Tablets 250 mg
70. Erythromycin Tablets 500 mg
71. Ethambutol Hydrochloride Tablets
72. Ferrous Sulphate and Folic Acid Tablets
73. Ferrous Sulphate Tablets
74. Fexofenadine Tablets 120 mg
75. Fexofenadine Tablets 180 mg
76. Frusemide Tablets
77. Furazolidone Tablets
78. Gatifloxacin Tablets 200 mg
79. Gatifloxacin Sesquihydrate Tablets 400 mg
80. Glibenclamide Tablets 5 mg
81. Gliclazide Tablets-II
82. Gliclazide Tablets 80 mg
83. Glidazide and Metformin Hydrochloride Tablets
84. Glimepiride and Pioglitazone Hydrochloride Tablets
85. Glipizide Tablets 2.5 mg
86. Glipizide Tablets 5 mg
87. Griesofulvin Tablets
88. Haloperidol Tablets
89. Hyoscine Butyl Bromide Tablets 10 mg
90. Ibuprofen and Paracetamol Tablets
91. Ibuprofen Tablets
92. Isosorbide Dinitrate Tablets
93. Ketotifen Fumerate Tablets 1 mg
94. Levamisole Hydrochloride Tablets 40 mg
95. Levodopa and Carvidopa Tablets
96. Loperamide Hydrochloride Tablets 2 mg
97. Lovastatin Tablets 20 mg
98. Mebendazole Tablets
99. Mefanamic Acid and Dicyclomine Tablets
100. Mefenamic Acid and Paracetamol Tablets
101. Meloxicam Tablets
102. Metformin and Glipizide Tablets
103. Methyl Dopa Tablets
104. Methylergometrine Maleate Tablets 0.5 mg
105. Metoclopramide Hydrochloride Tablets
106. Metoprolol, Dihydralazine and Hydrochlorothiazide Tablets
107. Metoprolol Tartrate Tablets
108. Metronidazole Tablets
109. Metronidazole, Furazolidone and Loperamide Tablets
110. Multivitamin Tablets -1
111. Multivitamin Tablets - II
112. Multivitamin With Iron Tablets
113. Nabumetone Tablets 500 mg
114. Nalidixic Acid Tablets 500 mg
115. Naproxen Tablets
116. Nicerbium Tablets 30 mg
117. Nifedipine Tablets 5 mg
118. Nimesulide Dispersible Tablets 100 mg
119. Nimesulide Flavoured Dispersible Tablets 100 mg
120. Nimodipine Tablets 30 mg
121. Nitrazepam Tablets
122. Nitrofurantoin Tablets
123. Norfloxacin Tablets
124. Ofloxacin Tablets
125. Paracetamol Tablets-I
126. Paracetamol Tablets-I I
127. Paracetamol and Diclofenac Sodium Tablets
128. Paracetamol, Caffeine and Chlorpheniramine Maleate Tablets
129. Paracetamol, Caffeine, Phenylephrine and Chlorpheniramine Tablets
130. Paracetamol, Diclofenac Sodium and Chlorzoxazone Tablets
131. Paracetamol, Ibuprofen and Chlorzoxazone Tablets
132. Pefloxacin Tablets 400 mg
133. Phenobarbitone and Belladonna Tablets
134. Phenobarbitone Tablets
135. Phenobarbitone, Papavarine and Aminophylline Tablets
136. Phenylbutazone Tablets 100 mg
137. Polyvitamin Tablets
138. Polyvitamin Tablets (Therapeutic)
139. Prednisolone Tablets
140. Promethazine Tablets
141. Propanthelene Bromide Tablets
142. Propranolol Hydrochloride Tablets
143. Pyrazinamide Tablets 500 mg
144. Pyrazinamide Tablets 750 mg
145. Pyrazinamide Tablets 1000 mg
146. Pyrimethamine and Sulphadoxine Tablets
147. Quinine Sulphate Tablets 300 mg
148. Ranitidine Tablets 300 mg
149. Ranitidine Hydrochloride Tablets 150 mg
150. Reserpine, Dihydralazine and Hydrochlorothiazide Tablets
151. Rifampicin and Isoniazid Tablets
152. Risperidone Tablets 1 mg
153. Risperidone Tablets 4 mg
154. Roxithromycin Dispersible Tablets 50 mg
155. Roxithromycin Tablets 150 mg
156. Salbutamol Tablets
157. Salbutamol, Etophylline and Dexamethasone Tablets
158. Salbutamol and Theophylline Sustained Release Tablets
159. Serratiopeptidase Tablets 10 mg
160. Sertraline Tablets
161. Sertraline Tablets 25 mg
162. Soluble Aspirin Tablets
163. Theophylline, Ephedrine and Phenobarbitone Sustained Release Tablets
164. Tinidazole and Norfloxacin Tablets
165. Tinidazole, Miconazole and Neomycin Tablets
166. Tinidazole, Miconazole and Neomycin Vaginal Tablets
167. Trifluoperazine Tablets
168. Trihexyphenidyl Hydrochloride Tablets
169. Trimethoprim and Sulphadiazine Tablets
170. Trimethoprim and Sulphamethoxazole DS Tablets
171. Vitamin B. Complex Tablets
172. Vitamin B. Complex Tablets (Prophylactic)
173. 173Vitamin B1 , B6 And B12 Tablets
174. Vitamin C Chewable Tablets