Drug Formulations Manual Third Edition

AUTHOR'S: D. P. S. Kohli and D. H. Shah
ISBN: 9798190018189
YEAR: 1991 – First Edition, 1993 – First Reprint, 1995 – Second Reprint, 1998 – Second Edition, 2000 – First Reprint, 2000 – Spanish Edition, 2001 – Supplement, 2003 – Second Reprint, 2005 – Third Edition, 2008 – Reprint
PAGES: 534
BINDING: Hard
LANGUAGE: English

ABOUT THE BOOK

Successful drug formulation development takes more than a great idea. It takes technology, know-how and manufacturing experience to find the best route for your product. It also takes regulatory expertise, a commitment from a team of dedicated people and GMP assets to meet your needs from development through commercial launch. DRUG FORMULATIONS MANUAL 3rd Edition can shed new light on how to get your drug formulations to market quickly and efficiently.
THERE ARE 420 PRODUCTS IN THIS BOOK COVERING SIX CATEGORIES OF DRUG FORMULATIONS
This long list of formulations include 174 Tablets, 69 Injectables, 79 Liquid Orals, 41 Capsules / Dry Syrups, 16 Eye / Ear Preparations and 41 Topical Preparations. All formulations are validated and based on actual production batches undertaken in various manufacturing facilities. The First Edition was published in 1991, Second Edition in 1998, Spanish Edition in 2000 and Supplement in 2001 along with their Reprints. Information on each product is covered under the following heads: Labelled Formula, Batch Size, Practical Yield, Ingredients and Batch Quantities, Manufacturing Specifications and Manufacturing Processes.

ABOUT THE AUTHOR'S

1. D.P.S. Kohli graduated in Pharmacy in 1954 with decades of practical manufacturing experience of drug formulations behind him. He also worked as a Pharmaceutical Consultant having set up over 50 drug formulation factories.
2. D.H. Shah graduated in Pharmacy in 1962 and was associated with the manufacture of all categories of drug formulations for more than 40 years.

CONTENTS

Preface to the third edition
Important Note
CHAPTER – 1: TABLETS
Acarbose Tablets
Albendazole Tablets
Albendazole Chewable Tablets 400 mg
Alprazolam Tablets 0.25 mg
Alprazolam Tablets 0.5 mg
Alprazolam Tablets 1 mg
Aluminium Hydroxide and Magnesium Trisilicate Tablets
Aluminium Hydroxide, Magnesium Hydroxide and Simethicone Tablets
Aminophylline Tablets
Amiodarone Tablets 100 mg
Amiodarone Tablets 200 mg
Amitryptyline Tablets 50 mg
Amlodipine Tablets
Amoxycillin Dispersible Tablets 125 mg
Amoxycillin Dispersible Tablets 250 mg
Amoxycillin Tablets
Amoxycillin Trihydrate and Clavulanate Tablets
Ampicillin, Cloxacillin and Lactobacillus Sporogenes Dispersible Tablets
Analgin and Dicyclomine Hydrochloride Tablets – I
Analgin and Dicyclomine Hydrochloride Tablets – II
Analgin Tablets
Ascorbic Acid Tablets 100 mg
Ascorbic Acid Tablets 500 mg
Aspirin, Paracetamol and Caffeine Tablets
Asprin, Chlorpheniramine Maleate and Phenylepherine Hydrochloride Tablets
Aspirin Tablets 300 mg
Atenolol Tablets 100mg
Atenolol Tablets 50 mg
Atorvastatin Tablets
Azithromycin Tablets 250 mg
B. Complex With Vitamin C Tablets
Betamethasone Tablets 0.5 mg
Betamethasone and Dexchlorpheniramine Maleate Tablets
Calcium and Vitamin D Tablets
Calcium, Vitamin D3 and L-Lysine Monohydrochloride Tablets
Captopril Tablets
Carbamazepine Tablets (Chewable Tablets)
Carbamazepine Tablets 250 mg
Cefadroxil Dispersible Tablets 125 mg
Cefadroxil Dispersible Tablets 250 mg
Cefadroxil Tablets 500 mg
Cetrizine and Pseudoephedrine Delayed Release Tablets
Chloroquin Phosphate Tablets
Chlorpheniramine Maleate Tablets
Chlorpromazine Tablets
Cimetidine Tablets 200 mg
Ciprofloxacin Tablets
Ciprofloxacin and Tinidazole Tablets
Clopidogrel Tablets
Compound Magnesium Trisilicate Chewable Tablets
Co-Trimoxazole Tablets
Co-Trimoxazole Tablets D.S
Dapsone Tablets 50 mg
Dexamethasone Tablets – I
Dexamethasone Tablets – II
Diazepam Tablets
Diclofenac Sustained Release Tablets 100 mg
Diclofenac Tablets 50 mg
Diethylycarbamazine Tablets
Digoxin Tablets
Domperidone Tablets 10 mg
Doxycycline Hydrochloride Tablets 100 mg
Drotaverine Hydrochloride Tablets
Enalapril Tablets
Enalapril Maleate Tablets 2.5 mg
Enalapril Maleate Tablets 5 mg
Ephedrine Hydrochloride Tablets
Erythromycin Tablets 100 mg
Erythromycin Tablets 250 mg
Erythromycin Tablets 500 mg
Ethambutol Hydrochloride Tablets
Ferrous Sulphate and Folic Acid Tablets
Ferrous Sulphate Tablets
Fexofenadine Tablets 120 mg
Fexofenadine Tablets 180 mg
Frusemide Tablets
Furazolidone Tablets
Gatifloxacin Tablets 200 mg
Gatifloxacin Sesquihydrate Tablets 400 mg
Glibenclamide Tablets 5 mg
Gliclazide Tablets – II
Gliclazide Tablets 80 mg
Glidazide and Metformin Hydrochloride Tablets
Glimepiride and Pioglitazone Hydrochloride Tablets
Glipizide Tablets 2.5 mg
Glipizide Tablets 5 mg
Griesofulvin Tablets
Haloperidol Tablets
Hyoscine Butyl Bromide Tablets 10 mg
Ibuprofen and Paracetamol Tablets
Ibuprofen Tablets
Isosorbide Dinitrate Tablets
Ketotifen Fumerate Tablets 1 mg
Levamisole Hydrochloride Tablets 40 mg
Levodopa and Carvidopa Tablets
Loperamide Hydrochloride Tablets 2 mg
Lovastatin Tablets 20 mg
Mebendazole Tablets
Mefanamic Acid and Dicyclomine Tablets
Mefenamic Acid and Paracetamol Tablets
Meloxicam Tablets
Metformin and Glipizide Tablets
Methyl Dopa Tablets
Methylergometrine Maleate Tablets 0.5 mg
Metoclopramide Hydrochloride Tablets
Metoprolol, Dihydrazine and Hydrochlorothiazide Tablets
Metoprolol Tartrate Tablets
Metronidazole Tablets
Metronidazole, Furazolidone and Loperamide Tablets
Multivitamin Tablets - I
Multivitamin Tablets - II
Multivitamin With Iron Tablets
Nabumetone Tablets 500 mg
Nalidixic Acid Tablets 500 mg
Naproxen Tablets
Nicerbium Tablets 30 mg
Nifedipine Tablets 5 mg
Nimesulide Dispersible Tablets 100 mg
Nimesulide Flavoured Dispersible Tablets 100 mg
Nimodipine Tablets 30 mg
Nitrazepam Tablets
Nitrofurantoin Tablets
Norfloxacin Tablets
Ofloxacin Tablets
Paracetamol Tablets-I
Paracetamol Tablets-II
Paracetamol and Diclofenac Sodium Tablets
Paracetamol, Caffeine and Chlorpheniramine Maleate Tablets
Paracetamol, Caffeine, Phenylephrine and Chlorpheniramine Tablets
Paracetamol, Diclofenac Sodium and Chlorzoxazone Tablets
Paracetamol, Ibuprofen and Chlorzoxazone Tablets
Pefloxacin Tablets 400 mg
Phenobarbitone and Belladonna Tablets
Phenobarbitone Tablets
Phenobarbitone, Papavarine and Aminophylline Tablets
Phenylbutazone Tablets 100 mg
Polyvitamin Tablets
Polyvitamin Tablets (Therapeutic)
Prednisolone Tablets
Promethazine Tablets
Propanthelene Bromide Tablets
Propranolol Hydrochloride Tablets
Pyrazinamide Tablets 500 mg
Pyrazinamide Tablets 750 mg
Pyrazinamide Tablets 1000 mg
Pyrimethamine and Sulphadoxine Tablets
Quinine Sulphate Tablets 300 mg
Ranitidine Hydrochloride Tablets 150 mg
Reserpine, Dihydralazine and Hydrochlorothiazide Tablets
Rifampicin and Isoniazid Tablets
Risperidone Tablets 1 mg
Risperidone Tablets 4 mg
Roxithromycin Dispersible Tablets 50 mg
Roxithromycin Tablets 150 mg
Salbutamol Tablets
Salbutamol, Etophylline and Dexamethasone Tablets
Salbutamol and Theophylline Sustained Release Tablets
Serratiopeptidase Tablets 10 mg
Sertraline Tablets
Sertraline Tablets 25 mg
Soluble Aspirin Tablets
Theophylline, Ephedrine and Phenobarbitone Sustained Release Tablets
Tinidazole and Norfloxacin Tablets
Tinidazole, Miconazole and Neomycin Tablets
Tinidazole, Miconazole and Neomycin Vaginal Tablets
Trifluoperazine Tablets
Trihexyphenidyl Hydrochloride Tablets
Trimethoprim and Sulphadiazine Tablets
Trimethoprim and Sulphamethoxazole DS Tablets
Vitamin B. Complex Tablets
Vitamin B.Complex Tablets (Prophylactic)
Vitamin B1, B6 And B12 Tablets
Vitamin C Chewable Tablets

CHAPTER – 2: INJECTABLES
Amikacin Sulphate Injection
Aminophylline Injection
Analgin Injection
Ascorbic Acid Injection 100 mg
Ascorbic Acid Injection 250 mg
Atropine Sulphate Injection
Buprenorphin Injection
Calcium Gluconate Injection
Chloramphenicol Injection
Chloroquine Phosphate Injection
Chlorpheniramine Maleate Injection – I
Chlorpheniramine Maleate Injection – II
Chlorpromazine Hydrochloride Injection 10 mg
Chlorpromazine Hydrochloride Injection 25 mg
Cimetidine Injection
Ciprofloxacin Lactate Infusion
Clindamycin Phosphate Injection
Cyanocobalamin Injection 1000 mcg - I
Cyanocobalamin Injection 1000 mcg – II
Cyanocobalamin Injection 500 mcg
Dexamethasone Sodium Phosphate Injection – I
Dexamethasone Sodium Phosphate Injection – II
Dextrose Injection 5% & 10% (Large Volume Intravenous Solution)
Dextrose With Sodium Chloride Injection
Diazepam Injection
Diclofenac Sodium Injection
Digoxin Injection
Electrolyte Maintenance I.V. Fluid Paediatric
Electrolyte Maintenance I.V. Fluid Solution
Etofylline and Theophylline Injection
Folic Acid and Niacinamide Injection
Fortified Procaine Penicillin For Injection
Frusemide Injection
Gastrointestinal Electrolyte Maintenance I.V. Fluid
Gentamycin Injection 40 mg
Gentamycin Injection 80 mg
Gentamycin Injection Paediatric
Hyoscine Butyl Bromide Injection
Lignocaine and Adrenaline Injection
Lignocaine Hydrochloride Injection
Menadione Sodium Bisulphite Injection
Methylergometrine Injection
Metoclopramide Injection
Metronidazole and Dextrose Infusion
Nandrolone Phenylpropionate Injection
Nikethamide Injection
Oxytetracycline Injection
Oxytocin Injection
Pam Injection
Papaverine Hydrochloride Injection
Pentazocine Injection
Phenytoin Sodium Injection
Prednisolone Sodium Phosphate Injection
Promethazine Hydrochloride Injection-I
Promethazine Hydrochloride Injection-II
Quinine Dihydrochloride Injection
Ranitidine Injection
Ringer Lactate I.V. Solution
Sodium Chloride Injection 0.9%
Thiamine Hydrochloride Injection
Triflupromazine Hydrochloride Injection-I
Triflupromazine Hydrochloride Injection-II
Trimethoprim and Sulphamethoxazole Injection
Vitamin B. Complex Forte Injection
Vitamin B. Complex Injection-I
Vitamin B. Complex Injection-II
Vitamin B. Complex Injection-III
Vitamin B Complex Injection-IV
Vitamin B1, B6, B12 Injection

CHAPTER – 3: LIQUID ORALS
Albendazole Suspension – I
Albendazole Suspension – II
Ambroxol Hydrochloride, Guaiphenesin, Pseudoephedrine and Chlorpheniramine Cough Syrup
Azatadine Maleate and Pseudoephedrine Sulphate Syrup
Azatadine Syrup
Azatadine, Pseudoephedrine and Paracetamol Syrup
Betamethasone Paediatric Drops
Bromhexine, Potassium Guaicol Sulphonate and Salbutamol Syrup
Broxhexine, Pseudoephedrine and Chlorpheniramine Cough Syrup
Calcium, L-Lysine and Vitamin D Suspension
Carbemazepine Liquid
Carbinoxamine and Dextromethorphan Cough Expectorant
Chloramphenicol Palmitate Oral Suspension-I
Chloramphenicol Palmitate Oral Suspension-II
Chloroquin Phosphate Syrup
Chloroquin Sulphate Tasteless Suspension
Ciprofloxacin, Tinidazole and Dicyclomine Suspension
Cough Expectorant-I
Cough Expectorant-II
Cough Expectorant-III
Cough Expectorant-IV
Cyproheptadine and L-Lysine Syrup
Cyproheptadine Hydrochloride Elixer
Cyproheptadine Hydrochloride Syrup
Dexchlorpheniramine Paediatric Syrup
Dextromethorpan, Bromhexine and Pseudoephedrine Cough Syrup
Disodium Hydrogen Citrate Syrup-I
Disodium Hydrogen Citrate Syrup-II
Erythromycin Stearate Suspension
Furazolidone, Kaolin and Pectin Suspension
Guaifenesin, Dexchlorpheniramine and Pseudoephedrine Expectorant
Ibuprofen and Paracetamol Suspension
Iron With Folic Acid Syrup
Iron With Minerals Syrup
Iron With Vitamins Syrup
Iron, Calcium and Vitamins Paediatric Tonic
Kaolin and Pectin Mixture
Levamisol Syrup
Loperamide Oral Solution
Magaldrate and Simethicone Suspension-I
Magaldrate and Simethicone Suspension-II
Malt Extract With Vitamins
Mebendazole Suspension
Metronidazole and Furazolidone Suspension-I
Metronidazole and Furazolidone Suspension-II
Metronidazole Suspension-I
Metronidazole Suspension-II
Miconazole Oral Gel
Multivitamin Drops-I
Multivitamin Drops-II
Multivitamin Drops-III
Multivitamin Drops With Minerals
Multivitamin Syrup
Multivitamin Syrup With Minerals
Nimesulide Suspension
Norfloxacin and Metronidazole Benzoate Suspension
Nystatin Suspension
Paracetamol and Promethazine Syrup
Paracetamol Oral Suspension
Paracetamol Syrup-I
Paracetamol Syrup-II
Paracetamol Syrup-III
Pheniramine Maleate Syrup
Potassium Liquid
Promethazine, Codeine and Ephedrine Cough Syrup
Pyrental Pamoate Suspension-I
Pyrantal Pamoate Suspension-II
Pyrantal Pamoate Suspension-III
Salbutamol, Bromhexine and Guiphenesin Cough Syrup
Trimethoprim and Sulphadiazine Suspension
Trimethoprim and Sulphamethoxazole Suspension D.S
Trimethoprim and Sulphamethoxazole Suspension S.S
Vitamin B. Complex Syrup
Vitamin B. Complex Syrup Prophylactic
Vitamin B. Complex Syrup Therapeutic
Vitamin B. Complex With Iron and Malt
Vitamin B. Complex With Iron and Vitamin C Syrup
Vitamin B. Complex With Vitamin C Syrup
Vitamin C Drops

CHAPTER – 4: CAPSULES AND DRY SYRUPS
Amoxycillin and Bromhexine Hydrochloride Capsules
Amoxycillin For Oral Suspension
Amoxycillin Trihydrate and Clavulanic Acid Dry Syrup
Amoxycillin, Cloxacillin and Lactobacillus Sporogenes Capsules
Ampicillin and Cloxacillin Capsules
Ampicillin, Cloxacillin and Lactobacillus Capsules
Ampicillin and Cloxacillin Dry Syrup
Ampicillin and Cloxacillin For Oral Suspension
Ampicillin Capsules 250 mg
Ampicillin Capsules 500 mg
Ampicillin For Oral Suspension
Celecoxib Capsules 200 mg
Cephalexin Capsules
Cephalexin Dry Syrup
Chloramphenicol Capsules 250 mg
Chlordiazdepoxide Capsules 5 mg
Clindamycin Capsules 150 mg
Clindamycin Capsules 150 mg
Erythromycin Dry Syrup 100 mg
Erythromycin Dry Syrup 125 mg -I
Erythromycin Dry Syrup 125 mg -II
Erythromycin Dry Syrup 200 mg (Sachets)
Erythromycin For Oral Suspension 100 mg
Fluoxetine Hydrochloride Capsules 20 mg
Gabapentin Capsules
Indomethacin Capsules
Iron, Protein and Vitamins Capsules
Lincomycin Capsules 500 mg
Mefenamic Acid Capsules
Oxytetracycline Capsules 250 mg
Paracetamol Capsules 500 mg
Piroxicam Capsules
Ramipril Capsules 2.5 mg
Rifampicin and Isoniazid Capsules
Rifampicin Capsules 150 mg
Rifampicin Capsules 450 mg
Sibutramine Hydrochloride Capsule
Tetracycline Capsules 250 mg
Vitamin B Complex Capsules
Vitamin B1, B6 and B12 Capsules
Vitamin B Complex With Vitamin C Capsules
Vitamin B12, Vitamin C, Folic Acid and Ferrous Fumerate Capsules

CHAPTER – 5: EYE AND EAR PREPARATIONS
Atropine Eye Ointment
Betamethasone Eye Drops
Betamethasone Eye Ointment
Betamethasone and Neomycin Eye/Ear Drops
Chloramphenicol and Dexamethasone Eye Drops
Chloramphenicol Ear Drops
Chloramphenicol Eye Drops
Chloramphenicol and Dexamethasone Eye/Ear Drops
Clotrimazole, Beclomethasone and Chloramphenicol Ear Drops
Dexamethasone Eye/Ear Drops
Gentamycin Eye Drops
Gentamycin and Betamethasone Eye/Ear Drops
Gentamycin Eye/Ear Drops
Hydrocortisone Eye Drops
Neomycin Eye Drops
Sulphacetamide Eye Drops 10%

CHAPTER – 6: TOPICAL PREPARATIONS
Aminacrine Antiseptic Cream
Betamethasone and Clotrimazole Cream
Betamethasone and Gentamycin Cream
Betamethasone and Gentamycin Ointment
Betamethasone and Iodochlorohydroxyquinoline Cream
Betamethasone and Neomycin Skin Ointment
Betamethasone and Salicylic Acid Lotion
Betamethasone and Salicylic Acid Ointment
Betamethasone Cream
Betamethasone, Clotrimazole and Gentamycin Cream
Betamethasone, Gentamycin, Tolnaftate and
Iodochlorohydroxyquinoline Cream
Betamethasone Gel
Chloroxylenol Solution
Clotrimazole Cream
Crotamiton Cream
Dexamethasone, Clotrimazole and Azidamphenicol Cream
Diclofenac Gel
Emollient Cream
Fluocinolone Cream
Fluocinolone Skin Lotion
Fluocinolone Lotion
Fluocinonide and Neomycin Gel
Gentamycin Cream
Hydrocortisone Cream 1%
Ketoconazole Cream
Mephenesin, Methylnicotinate and Capsicum Oleoresin Ointment
Miconazole and Hydrocortisone Gel
Miconazole Gel
Miconazole Ointment
Miconazole Solution
Miconazole Talc Powder
Mometasone Furoate Lotion
Neomycin and Bacitracin Ointment
Nitrofurazone Cream
Povidone Iodine Gargle Solution 1%
Povidone Iodine Ointment
Povidone Iodine Topical Solution
Sisomicin Cream
Tolnaftate Cream
Tolnaftate Solution
Triamcinolone Acetonide Gel

Therapeutic Index
Active Ingredients Index
Advertisers Index